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UMR 7286 - Centre de Recherche en Neurobiologie et Neurophysiologie de Marseille


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Mothet Jean-Pierre

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téléphone : 04 91 69 87 69

statut : Chercheur (CR)

fonction : Responsable d'équipe 

Jean-Pierre Mothet is a former PhD student of Dr Ladislav Tauc in Gif-sur-Yvette and obtained his PhD in Neuroscience in 1996 from the university of Pierre and Marie Curie. After his Ph.D, he moved to the USA to carry out postdoctoral training in the laboratory of Professor Solomon H. Snyder at The Johns Hopkins School of Medicine in Baltimore. There he worked at deciphering the functions and the synthesis pathway of brain D-amino acids with a special focus on D-serine. He helped in identifying serine racemase the enzyme that synthesizes D-serine and discovered that D-serine rather than glycine is the endogenous coagonist of synaptic N-Methyl D-Aspartate subtype of glutamatergic receptors in the hippocampus. In 1999, he took a second postdoctoral position in the laboratory of Professor Jacopo Meldolesi in Milano, Italy, in the Department of Neuroscience at Vita-Salute San Raffaele University where he worked on the molecular mechanisms of regulated and constitutive exocytosis. In 2000, he took his first research appointement at the French National Center for Research (CNRS) in the laboratory of Dr. Maurice Israel then of Gérard Baux at the Institute of Neurobiology Alfred Fessard in Gif-sur-Yvette, and in 2006, he moved to Bordeaux at the Neurocentre Magendie. In 2011, he was appointed as the leader of ’Gliotransmission and Synaptopathies’ team at the Centre de Recherches en Neurobiologie et Neurophysiologie de Marseille. In 2012, he was elected President of the French Club of Glial Cells. He is the member of the Editorial boards of Frontiers in Synaptic Neuroscience and of PlosONE.
For more informations, please see http://cvscience.aviesan.fr/cv/1485/jean-pierre-mothet


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